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Mice harboring the FXN I151F pathological point mutation present decreased frataxin levels, a Friedreich ataxia-like phenotype, and mitochondrial alterations
However, it has been proposed that HTyr may confer additional antioxidant protection by increasing the endogenous defense systems against an oxidative stress, by activating different cellular signaling pathways [21] (see Figure 1)
Feng Z, Zhou J, Liu Y, Xia R, Li Q, Yan L, et al
[] Nevertheless, the nonselective clearance of uremic toxins can positively impact sepsis
