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The authors of the latter studies concluded that the reduced mitochondrial respiration led to enhanced apoptosis and postulated that this immunosuppressive effect of E2 explained why post-menopausal women exhibit increased osteoclast activity and bone resorption (197199)

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[DOI] [PubMed] [Google Scholar] 140.Lu C, He JC, Cai W, Liu H, Zhu L, Vlassara H

The restraints for the N-terminal lipid modification of Cagri were generated by the electronic Ligand Builder and Optimization Workbench (eLBOW) in PHENIX
