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Interfaces 136 YanJ.ZhouW.JiaZ.XiongP.LiY.WangP.et al (2018)

Despite the preclinical evidence supporting evaluation of IGF-targeted and endocrine therapy combinations, treatment with ganitumab plus the AI exemestane or ER antagonist fulvestrant did not improve PFS in women with previously treated hormone receptor-positive breast cancer, and OS was lower in the combination group versus endocrine treatment alone [197, 200]

Mild dehydration mimics hunger, so people snack when really they need fluids

In addition, they provide a rationale for additional larger placebo-controlled trials in both healthy and diseased individuals aimed at assessing the potential therapeutic efficacy of liposomal GSH