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Data availability All data are available upon request from the authors and summary data will be made available via the UK Biobank ( Funding This work was supported by Health Data Research UK, an initiative funded by UK Research and Innovation, Department of Health and Social Care (England) and the devolved administrations and leading medical research charities

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The production dosage forms involve powder/premix, terminally sterilized small-volume injection (including Chinese medicine extraction)/ terminally sterilized large-volume non- Intravenous injection (including traditional Chinese medicine extraction)/oral liquid solution (including traditional Chinese medicine extraction), non-chlorine disinfectant (liquid), feed additives(Probiotics Green)/antibiotic tablets bolus and Originally created China's leading Chinese medicine antiviral preparations, animal Chinese medicine extract preparations such as Toad venom and Cantharidin

Competitive endogenous RNAs (ceRNAs) act as sponges for miRNAs, ceRNAs can bind to miRNAs and reduce the abundance of miRNAs in the cell, thus reducing the inhibitory effect of miRNAs on target genes