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Zhao J, Cai X, Gao W, Zhang L, Zou D, Zheng Y, et al

To determine whether GSSG-induced TNF hepatotoxicity is associated with inhibition of the NF-B signaling pathway, we first examined the effects of H 2 O 2 , BCNU, and diamide treatment on TNF-stimulated NF-B activation
After this "Point of Diminishing Returns," higher BACs will result in fewer and fewer positive effects

Although selenium was not measured in this study, adequate nutritional intake of selenium could potentially mask other differences between genotypes in this population
