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Generation of a set of isogenic, gene-edited iPSC lines homozygous for all main APOE variants and an APOE knock-out line

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Reducing the consumption of carnitine-rich foods and supplements, such as red meat (pork, lamb, and beef), liver, and offal, can also be beneficial [4,19]

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people with alcohol use disorder, which decreases folate absorption and accelerates its breakdown

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Many molecular inhibitors and drugs, such as antidiabetic and anti-obesity drugs, antibiotics, pre/probiotics, caspase inhibitors, and CCR2/5 antagonists, are currently under clinical investigation for NAFLD or NASH treatment [228]

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