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JCI Insight 6 , e145207 (2021)

(PubMed) Wen YY, Yang SJ, Zhang JX, Chen XY

As the first Rbs, we focused on berberine 13,14 because it selectively binds to G-quadruplex (G4) structures formed from guanine-rich sequences, which play an important role in gene expression regulation and are promising drug targets 15,16,17,18

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