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In contrast, in the randomized, placebo-controlled study in 251 patients with STEMI undergoing primary angioplasty discussed in the previous section, high-dose NAC (1200 mg IV bolus twice daily intravenously for 48 hours) was associated with a numerically lower incidence of CIN in patients treated with NAC versus placebo (14% vs

This reflects its significant presence in pharmaceutical and research sectors

The subjects receiving most of their energy as fat had a lesser IGF-I response to GH, whereas subjects receiving the same caloric intake as carbohydrate demonstrated greater increases in IGF-I to GH stimulation (70, 71)

Somit bleibt die klinische Aussagekraft eingeschrnkt insbesondere hinsichtlich Sicherheit und Langzeiteffekten