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In addition, we observed no effect of LC on thigh muscle volume following 24 weeks of RET combined with leucine supplementation

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On its own, phentermine produces modest weight loss of 3-5% of body weight

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2.4 Methodological Quality Appraisal To investigate the methodological quality of the evaluated studies, we used the Cochrane risk of bias tool for randomized trials (version 2, RoB 2, London, United Kingdom), which consists of six main items for evaluating study quality: the randomization process, intervention adherence, missing outcome data, outcome measurement, selective reporting, and the overall risk of bias (Sterne et al., 2019)

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