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In the setting of high ROS, as is seen with G6PD-inhibition, heme production has been shown to be impaired 137
[DOI] [PubMed] [Google Scholar] [133].Windrem MS, Schanz SJ, Guo M, Tian GF, Washco V, Stanwood N, et al
13( S )-HODE has been shown to restore apoptosis in a human colorectal cancer cell line 553 and to inhibit cell growth in a dose-dependent manner in breast cancer cell lines via down-regulation of PPAR
