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Some traditional Chinese medicine are proved be able to lower TMAO concentrations, such as Alisma orientalis beverage (Zhu et al., 2020), Ginkgolide B (Lv et al., 2021), Berberine (Obeid et al., 2017)

Currently, the drugs used for the treatment of this disease are based on the administration of anti-inflammatory and immunosuppressive drugs for long periods, the disadvantage of these is that they are expensive, and have a low degree of effectiveness, with several side effects [12,13], unlike therapies based on a nutritional approach have proven to be effective for the treatment and prevention of chronic diseases, without causing side effects [5]