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Do not use GHK Cu if the patient has: An allergy to copper or peptides Wilsons disease or other copper handling issues Active cancer (GHK Cu affects growth pathways) Pregnancy or breastfeeding (no safety data exists) Use extra caution with: History of metal sensitivity Autoimmune conditions Other peptides or growth factors being used at the same time Side effects people sometimes report: Mild redness or itchiness at the injection spot (most common) Headache or tiredness (rare, usually gone in a day) Metallic taste in the mouth (very rare, passes quickly) If a patient has anything beyond mild local irritation, stop

Iron-chelating agents protected RGCs from NMDA excitotoxicity-mediated cell death by reducing intracellular iron levels and alleviating oxidative stress in rodents (318, 319)

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