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Tumor cells with mesenchymal phenotype are resistant to the dual IGF-IR/InsR inhibitor linsitinib, due to the decreased expression of IGF2 and InsR, and phosphorylation of IGF-IR/InsR in these cells [182]
doi: 10.3389/fneur.2023.1326738 [DOI] [PMC free article] [PubMed] [Google Scholar] 51
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In the same way, polydopamine (pDA) coating on the surface of particles can induce immobilization of some serum adhesives and adsorption of some cell types [52]
