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10.1001/jamanetworkopen.2020.25850 JAMA Netw Open

Certain strains, including Lactobacillus acidophilus , inhibit multiple proinflammatory pathways, such as PI3KAKTNF-B, via their metabolites ( In summary, by modulating immune-cell function, rebalancing lymphocyte subsets, and reprogramming core signaling networks, probiotics operate through an integrated cellular-to-molecular network to correct immune dysregulation in UC, offering a multi-target strategy to restore intestinal immune homeostasis

This interaction improves mitochondrial function, facilitates ROS clearance, diminishes apoptosis, mitigates liver injury, and decelerates the progression of NAFLD [38]

182 Excessive consumption of alcohol was also associated with increased gastrointestinal symptoms in individuals with IBS, although only women were surveyed in this population study