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Description
May not be tolerable enough for widespread use
17 families are described, most drugs are metabolized by the CYP 3A4 and CYP 2D6 systems, microsomal oxidation system, mitochondrial amino oxidase, cytoplasmic alcohol and aldehyde dehydrogenase, xanthine oxidase, peroxidase, reductase (endoplasmic reticulum and cytoplasm), hydrolase (e.g
Brain tissue contains the second-highest percentage of fat after adipose tissue, and fat makes up half of the brains dry weight (88)
ERR is a nuclear receptor that shares significant DNA sequence homology with ER, although E2 is not considered its endogenous ligand 51
