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[DOI] [PubMed] [Google Scholar] 101.Thornburg LP, Crawford SJ

MOTS-c (mitochondrial ORF of the 12S rRNA type-c) is an MDP that promotes metabolic homeostasis, in part, via AMPK 15,16 and by directly regulating adaptive nuclear gene expression following nuclear translocation 17,18

10.3389/fncel.2014.00396 Front

The current understanding based on studies from several groups is that hydroperoxide-generating enzymes called lipoxygenases (LOXs) can initiate ferroptosis by generating lipid peroxides
