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While ER-mitochondrial crosstalk has been shown to play a role in the development of neurodegenerative diseases such as Parkinsons disease, Huntingtons disease, amyotrophic lateral sclerosis, and Alzheimers disease, among others 7,8,9,10 , there has been significantly less research regarding the role of ER-mitochondrial crosstalk in the development of FECD

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