glutathione is synthesized from iron Metabolism - an overview Natural Compounds and Glutathione: Beyond
Description
Ther., 210: 247-251

Class III peroxidases are activated in proanthocyanidin-deficient Arabidopsis thaliana seeds

others (like celastrol, a large triterpene) might not cross readily but can influence the CNS indirectly via peripheral immune modulation [110]

So why did the Pauling and Mayo Clinic trials have different results
