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doi: 10.1523/JNEUROSCI.1317-11.2011

A review of injectable polymeric hydrogel systems for application in bone tissue engineering
In vitro and in vivo effects of PDGF-BB delivery strategies on tendon healing: a review

However, recent simulation studies demonstrate that either dosing method results in a similar degree of PK and PD variability suggesting that normalization of dose by body weight is an unnecessary step.36, 37, 38 Regardless of the option taken, the strategy should provide reduced interpatient variability to optimize therapeutic effect coupled with convenience, compliance, and costeffectiveness
