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Detailed immunohistochemical investigations in sural nerve biopsies obtained from diabetic patients with DPN point to an activation of inflammatory pathways induced via elevated advanced glycation end products (AGE), ultimately resulting in increased oxidative stress

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In addition, we have reported that thrombin affects synaptic transmission in hippocampal CA3 neurons by enhancing both frequency and amplitude of mEPSCs, while reducing frequency and amplitude of mIPSCs (Maggio et al., 2013b)

Iodine plays a crucial role in the synthesis of thyroid hormones, specifically T4 (tetraiodo-L-thyronine) and T3 (triiodo-L-thyronine) ( There are 36 known radioactive isotopes of iodine, with particular attention given to 129 I and 131 I ( 129 I in precipitation increased by four orders of magnitude ( In offshore surface waters near Fukushima, 129 I concentrations ranged from 0.002 to 0.133 pg