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Description
Ablation of all NR4A members prevents terminal exhaustion of CD8 T cells, resulting in the replacement of exhausted cells with effector-like T cells characterized by low PD-1 and Tim-3 expression [44]
Unlike apoptosis, the assembly of inflammasomes that trigger pyroptosis is initiated by proteins that sense specific DAMPs or PAMPs and subsequently form an oligomeric scaffold
10.1126/science.1185988 119 NystoriakM
Furthermore, other antioxidant agents, such as vitamin E (73), thioredoxin (74), and aldehydeketone reductase family 1, also play certain roles in ferroptosis (75)
