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To decongest blood vessels and thus reduce bluish dark circles, it can be beneficial to apply cosmetic active ingredients that have draining properties , such as caffeine, vitamin K or even immortelle essential oil

The function of IEB depends on the apical junction complexes (AJC), composed of tight junctions (TJ), adherent junctions (AJ) and desmosomes, can control the entry of gut microbiota into intestinal connective tissue, prevent antigens from passing through IEB (Alonso et al., 2014)

Diabetes in Cushing syndrome: basic and clinical aspects