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doi: 10.2337/diabetes.49.2.143

It also suggests talking to your doctor first if you: have kidney or liver disease have any type of infection are receiving treatment that affects bone marrow Encourage clients to talk with their doctor before trying to achieve weight loss with vitamin B12 injections

[15] Serious but infrequent events-such as angioedema, bronchospasm, hypotension, or urticaria-reflect IgE-mediated hypersensitivity and may require desensitization or substitution with hydroxocobalamin