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Our results indicate kidney problems can develop silently and gradually over time, eroding kidney function and leading to long-term kidney damage or even renal failure

Together, we believe that this experimental tumor model recapitulates several features of spontaneous glioma observed in most clinical contexts, though not all, and has helped us to address our question related to the effectiveness of this drug in glioma cell proliferation and metastasis

APE exhibited low toxicity toward RAW264.7 cells
