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55 JAK1/STAT3 signaling pathway Signal transducer and activator of transcription 3 (STAT3) is a transcription factor (TF) that, on phosphorylation by JAK1 tyrosine kinase, forms homo or heterodimers to modulate cell proliferation, apoptosis and cell motility
In contrast the expression levels of MAPK-8, TRAF-4, and TRAF-6 genes were significantly down-regulated in G 2 and G 3 , respectively
& Reglinski, J
HisF is involved in histidine biosynthesis catalyzing the closure of the imidazole ring 33
