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The cytochrome P450 (CYP450) enzymes, predominantly found in the human liver, are a class of heme monooxygenases that play a significant role in mediating ER ROS production

In contrast, inactivation of ABCC1 had no impact on cell proliferation in multiple AML cell lines in the absence of drugs, which is in line with previous data 68 , and ABCC1 inhibition did not sensitize AML cells to various other anticancer drugs that are used to treat AML, including the chemotherapeutic Cytarabine, FLT3-inibitors and IDH inhibitors

doi: 10.1517/14656566.8.6.873

To avoid deficiency, regularly eat foods high in vitamin B6, such as chicken breast, banana, or avocado