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The primary goal of titration is to reduce the severity of gastrointestinal side effects, such as nausea, vomiting, bloating, or diarrhea, which are most common when you start treatment or increase the dosage

Eligibility criteria included peer-reviewed primary studies and regulatory documents reporting mechanistic, preclinical, or clinical data in English

DSIP functions through mechanisms that are not fully characterized but appear to involve modulation of sleep-wake regulatory centers in the brain and interactions with various neurotransmitter systems

You can also engage directly with component representatives through the DoWs SBIR/STTR page, which lists all 12 component websites and points of contact