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Description
As a result, the systemic exposure to the unconjugated form is typically low and highly sensitive to individual differences in metabolic enzyme activity (e.g., UGTs and SULTs), leading to marked inter-individual variability

Milara J, Peir T, Serrano A, Guijarro R, Zaragoz C, Tenor H, Cortijo J (2014) Roflumilast N-oxide inhibits bronchial epithelial to mesenchymal transition induced by cigarette smoke in smokers with COPD
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L., Moguilevsky, N
