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Furthermore, after severe COVID-19, patients were noted to lack surface CD21 (involved in the transduction of the surface B cell receptor-linked activating signal) typical of activated self-reactive B cells (86)

Sections were immersed in a buffer containing terminal deoxynucleotidyl transferase and digoxigenin-labelled nucleotides for 2 h at 37 C

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in the IV syringe or bag) this phenomenon happens even faster than in plasma or tissue samples when additives are introduced due to lack of in-vivo enzymes