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The exact mechanisms of IIM pathogenesis remain unknown, but it is widely believed to result from the interplay of genetic, environmental, immune, and non-immune factors (endoplasmic reticulum stress, oxidative stress, abnormal autophagy regulation, hypoxia, and angiogenesis) [221]

Jeske, R., Albo, J., Marzano, M., Bejoy, J

Research has shown that NAD+ levels tend to decline with age, and some studies suggest that boosting NAD+ levels through supplementation might have potential benefits for certain aspects of ageing

10.1093/jxb/erac442 84 LuJ.GuoQ.ZhaoH.LiuH
