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Toll-like receptor stimulation in cardiomyoctes decreases contractility and initiates an NF-kappaB dependent inflammatory response

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Factors such as population diversity, socioeconomic status, racial differences, and sample size may contribute to these inconsistencies

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In line, Grx2 knockout mice resemble phenotypes of mice expressing a hypomorphic Gpx4 allele, such as lipid peroxidation in the brain or loss of parvalbumin-positive neurons [71]

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