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They exhibited increased intraocular pressure and mydriasis, degeneration of retinal ganglion cells, optic nerve head excavation and reduction in optic nerve thickness, generalized severe irregularity of retinal vessels, faint presentation of choroidal vessels, and severe optic nerve disc atrophy

Sep - Oct 2020;14(5):1307-1314

Would starting BPC-157 first and letting the receptor upregulation build up before adding the secretagogue produce a bigger effect than running them simultaneously from day one

Some portion of intranasally administered peptides may reach the central nervous system through the olfactory pathway, bypassing the blood-brain barrier