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& Jorgenson, E
Nutrition and Metabolism 2010;7(30):1-14
The molecule is structurally modified with an N-terminal trans-3-hexenoyl group, which dramatically reduces its susceptibility to dipeptidyl peptidase IV (DPP-IV) degradation, the enzyme that breaks down natural GHRH
At the same time, studies in vitro have shown that L-carnitine inhibits the activity of matrix metalloproteinases MMP-1 and MMP-2, enzymes that contribute to the degradation of the dermal matrix under oxidative stress
