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In the U.S., CVD is the leading cause of death, constitutes 17% of healthcare costs, and is estimated to increase in prevalence by ~10% and direct costs by almost three-fold over the next 20 years under current CVD prevention and treatment regimes [2]

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Regular physical activity, especially during fasting periods or before meals, increases fatty acid mobilization and creates the conditions where enhanced carnitine-mediated transport could theoretically make a difference