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In the case of cancer cells, hypoxia leads to significant metabolic changes that result in a substantial increase in lactate concentration, ranging from 10 to 30 mM

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In a randomized controlled trial that included 109 healthy men with mildly elevated cholesterol levels, 150 mg of aronia polyphenols daily for 90 days reduced total and LDL-cholesterol levels in men under 40 years of age, but not those 40 years and older, and had no effects on measures of glucose metabolism, blood pressure, oxidative stress, or inflammation

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