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A study has shown benefits for combination treatments for dark circles

doi: 10.1016/j.freeradbiomed.2019.10.011

After its made in the skin as vitamin D3 (cholecalciferol), it becomes converted by the liver and kidney into a secosteroid hormone (calcitriol) that has receptors in practically all our tissues

[DOI] [PMC free article] [PubMed] [Google Scholar] 64.Li Q., Engelhardt J
