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Precision medicine approaches should enroll participants based on biological signatures rather than broad diagnostic categories, including glutathione status, lactate to pyruvate ratios, N acetyl aspartate, NRF2 related profiles, electron transport chain complex activity, and the presence of folate receptor alpha autoantibodies in cerebral folate deficiency

Echocardiography including LVEF, global longitudinal strain and dimensions were normal apart from left ventricular hypertrophy with normal systolic function in one young male

While stored in muscle, the brain, and sperm, it primarily comes from animal products, with meat being the optimal source

Febbraio, M