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Under physiological conditions, ROS are generated in the heart mainly from the mitochondrial electron transport chain, nitric oxide synthases (NOS), NADPH oxidases (NOX), and xanthine oxidase (XO) in small quantities [7, 8]

Inhibition of GT in melanoma cells significantly increased the radiosensitivity of a high GT variant (Prezioso et al., 1994b)

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By modulating this pathway, researchers explore how it may support investigations into metabolic energy balance, adipose response, and overall metabolic health