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10.1007/s11427-017-9047-4 110 ZhangZ.LaiD.WangL.YuP.ZhuL.GuoB.et al (2014)

You're hitting mitochondrial health from two angles simultaneously: MOTS-C improves mitochondrial efficiency and increases fat oxidation NAD+ replenishes the coenzyme required for ATP synthesis For anyone over 40 who's training seriously, this pairing addresses two of the most significant age-related performance bottlenecks at once

Muscle protein breakdown increases to help provide energy and amino acids for the synthesis of proteins and othere nitrogen-containing compounds needed to produce these cells