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43 In view of the potential for AEs associated with biologic therapy, the American College of Rheumatology position statement encourages administration of biologics to patients with rheumatoid arthritis at a treatment center with specially trained practitioners instead of at-home treatment

Among the mechanisms envisaged to occur to explain their toxicity against cells in culture are the release of toxic cadmium ions through their dissolution by the acidic environment of cell lysosomes [195] and their ability to generate and trap free radicals [196,197,198,199]

19 Rates of urate-lowering medicine dispensing in 2024 were 1.8 times higher in Mori and 2.5 times higher in Pacific people compared with those of European/Other ethnicity ( Figure 1B )

Leonardi C, Matheson R, Zachariae C, Cameron G, Li L, Edson-Heredia E,
