curcumin glutathione s transferase mediates depletion via metal–organic framework nanocarriers to enhance cisplatin chemosensitivity on esophageal cancer | Discover Nano The Multifaceted Role of Glutathione
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Similarly, in subarachnoid hemorrhage, curcumin demonstrates neuroprotective effects by suppressing neuronal ferroptosis through the modulation of nuclear factor erythroid 2-related factor 2/Heme Oxygenase-1 signaling (Xu et al., 2025b)
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This creates a feedback loop in which microbiota restoration, metabolic regulation, and immune modulation act synergistically to restrain tumorigenesis
