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[2] Other conditions giving rise to malabsorption include surgical removal of the stomach, chronic inflammation of the pancreas, intestinal parasites, certain medications such as long-term use of proton pump inhibitors, H2-receptor blockers, and metformin, and some genetic disorders

How you apply it also makes a difference

Glycine can be synthesized via the interconversion of serine through serine hydroxymethyltransferases with concomitant conversion of tetrahydrofolate (THF) into 5,10methyleneTHF

10 We have suggested 10 that arguments for and against autism as an epidemic (or pandemic) can only be resolved (a) if a specific trigger for autism is found, facilitating the elimination of autism