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The meta-analysis of Heydarpour et al., which reviewed five high-quality trials involving 448 women with PCOS, showed that cinnamon supplementation decreased fasting blood sugar, fasting insulin, and HOMA-IR [200]

ACO1 expression appears to be strongest in the pericarp, septa and columella of orange to red fruit, matching the tissue-specific ACO in vitro activity reported by Van de Poel et al

however, neutrophilic infiltrates were also found in more than 40% of cats with concurrent IBD

It also increases the risk of cardiovascular and metabolic complications such as hypertension, dyslipidemia, obesity, and type 2 diabetes mellitus [6]
