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Biomedicines 12 , 2123 (2024)
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doi: 10.1016/j.nut.2016.01.010 91 ShiLLinQLiXNieYSunSDengXet al
Excessive amounts of APAP metabolism in the liver generate a toxic intermediate, N-acetyl-p-benzoquinone imine (NAPQI), mainly through the activity of cytochrome P450 enzymes CYP2E1 and CYP1A2
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