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The available in vitro and in vivo animal studies have limited their focus on the global osteogenic output

Having a clinician who understands both the pharmacology and the real-world variability can make the difference between sticking with a protocol that's working (even if slowly) and abandoning it prematurely

12 Targeted exercises may help in cases with residual muscle weakness or dysfunction, and specialized eyelid surgeries, such as customized weighted implants and horizontal lid tightening, may be indicated in cases of persistent inability to fully close the eyelid

The wound healing process itself is complex and heterogeneous, relying on a coordinated interplay of inflammatory mediators, blood components, extracellular matrix elements, and connective tissue cells [15]