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Description
Skipping of exon 14 removes Y1003, a key phosphorylation site required for CBL-mediated c-MET ubiquitination and subsequent degradation, resulting in aberrant c-MET accumulation and prolonged signaling, thereby driving unchecked cellular proliferation [45,46,47,48]
To assess treatment response, the study uses advanced imaging tools including intestinal ultrasound (IUS) and magnetic resonance enterography (MRE)
The most common mistake researchers make with 5-Amino-1MQ isn't the reconstitution
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