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The most common include: Nausea Vomiting Diarrhea Decreased appetite Constipation These symptoms often occur when starting the medication or increasing the dose and typically improve over time as the body adjusts

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When pathogens are detected, through mechanisms like pathogen-associated molecular patterns (PAMPs), damage-associated molecular patterns (DAMPs), or through detection of pathogen toxins, mucus-producing cells can dramatically increase mucin production and secretion (Rada et al., 2011