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doi:10.1038/sj.mp.4001790

Rome FI, Hughey CC

Besides Gpx1, Gpx4 displays preference for lipid hydroperoxides ( Figure 3 ), and hence plays a key role in protecting phospholipids, cholesteryl esters and cardiolipin and defense against apoptosis and maintenance of ETC and OXPHOS (Cole-Ezea et al., 2012)

Overall, the authors concluded that NAC might be useful as a chemopreventive agent
