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Additionally, another study conducted in 2020 found that apart from directly causing cell death, DDC can effectively stimulate immunogenic cell death (ICD) in cancer cells, leading to the modification of the immunosuppressive tumor microenvironment (TME)

While previous studies have highlighted DDX3X multifaceted roles in lung cancer progression and its potential as a therapeutic target, a comprehensive understanding of its involvement in lung cancer necessitates further in-depth investigations

J Clin Investig 118(3):868878

Researchers outside the U.S
