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This mechanism is thought to account for the rewarding effects of 9 -THC and other cannabinoid drugs, and is also likely to be a prominent mechanism through which eCBs contribute to brain mechanisms of reward

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Fellner L, Irschick R, Schanda K, Reindl M, Klimaschewski L, Poewe W, et al
Measurable body composition changes generally appear by weeks 24